Ganjam V Kalpana Selected Research

Rhabdoid Tumor (Rhabdoid Tumors)

1/2021	Inhibition of nuclear export restores nuclear localization and residual tumor suppressor function of truncated SMARCB1/INI1 protein in a molecular subset of atypical teratoid/rhabdoid tumors.
5/2011	Aurora A is a repressed effector target of the chromatin remodeling protein INI1/hSNF5 required for rhabdoid tumor cell survival.
11/2010	Potent inhibition of rhabdoid tumor cells by combination of flavopiridol and 4OH-tamoxifen.
7/2008	Design, synthesis of novel peptidomimetic derivatives of 4-HPR for rhabdoid tumors.
7/2008	Design and synthesis of 4-HPR derivatives for rhabdoid tumors.
1/2008	Rhabdoid tumor growth is inhibited by flavopiridol.
8/2007	INI1 induces interferon signaling and spindle checkpoint in rhabdoid tumors.
8/2005	Genetic ablation of Cyclin D1 abrogates genesis of rhabdoid tumors resulting from Ini1 loss.
8/2002	Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5.
1/2002	A masked NES in INI1/hSNF5 mediates hCRM1-dependent nuclear export: implications for tumorigenesis.

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Ganjam V Kalpana Research Topics

Disease

10	Neoplasms (Cancer) 01/2021 - 01/2002
10	Rhabdoid Tumor (Rhabdoid Tumors) 01/2021 - 01/2002
3	Carcinogenesis 07/2008 - 01/2002
2	Infections 01/2017 - 01/2014
1	Residual Neoplasm 01/2021
1	Neuroinflammatory Diseases 01/2014
1	Neurocognitive Disorders (Clerambault Syndrome) 01/2014
1	Schwannomatosis 03/2013
1	Breast Neoplasms (Breast Cancer) 09/2011
1	Glioma (Gliomas) 09/2011

Drug/Important Bio-Agent (IBA)

7	Cyclin D1IBA 09/2011 - 08/2002
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2002
3	FenretinideIBA 09/2011 - 07/2008
3	alvocidib (flavopiridol)IBA 01/2011 - 01/2008
2	Pharmaceutical PreparationsIBA 01/2017 - 01/2014
1	SMARCB1 ProteinIBA 01/2021
1	selinexorIBA 01/2021
1	DNA (Deoxyribonucleic Acid)IBA 01/2017
1	Dopamine (Intropin)FDA LinkGeneric 01/2014
1	afimoxifene (hydroxytamoxifen)IBA 11/2010
1	Biological ProductsIBA 07/2008
1	Alkenes (Olefins)IBA 07/2008
1	RetinoidsIBA 07/2008
1	PeptidomimeticsIBA 07/2008
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2008
1	CyclinsIBA 01/2008
1	InterferonsIBA 08/2007
1	Complementary DNA (cDNA)IBA 08/2007
1	Adenosine Triphosphate (ATP)IBA 08/2002
1	IntegrasesIBA 01/2002

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 03/2013